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The UK-wide Principle Trial (Platform Randomised Trial of Treatments on the Community for Epidemic and Pandemic Illness) funded by the National Institute for Health Research (NIHR) is looking at early treatment for COVID-19 to prevent ill health and hospitalisation. It is evaluating a number of potential treatments. More information about this trial is at: Join the PRINCIPLE Trial — PRINCIPLE Trial

The Scottish Government Chief Scientist Office is also funding a trial of a potential anti-viral medicine as an early treatment of COVID-19. More information about this trial is at: GETAFIX - Glasgow Early Treatment Arm FavipiravirX (getafix-trial.org.uk)

A well-functioning care sector will be vital in delivering a prosperous wellbeing economy for Scotland – one that is strong, fair and green.

The Scottish Government’s Economic Recovery Implementation Plan published in August 2020, acknowledged the care sector as key economic infrastructure and recognised that investment in care yields significant economic returns.

The Scottish Government has committed to delivering a 10 year National Strategy for Economic Transformation in Autumn 2021. This strategy will set out the steps we will take to deliver a stronger, fairer and greener economy.

The Scottish Government is not able provide this information; this would require minute by minute analysis of all data held for the specific areas and all surrounding areas as the Scottish Ambulance Service operates a national service.

Vehicle cover provided is dynamic and fluid with ever changing variables.

The Scottish Government met with the EIS on 8 September for their bi-annual meeting with the Cabinet Secretary for Education and Skills. Education recovery, Staffing and COP26 were discussed.

The Scottish Government has regular meetings with the EIS to discuss a range of issues relating to education.

Information on how many people have received a dementia diagnosis in each year since 2007, broken down by NHS board, is not collected or held centrally.

I refer the member to the answer to question S6W-02419 on 21 September 2021. All answers to written Parliamentary Questions are available on the Parliament's website, the search facility for which can be found at https://www.parliament.scot/chamber-and-committees/written-questions-and-answers

Local authorities are independent corporate bodies with their own powers and responsibilities, separate from the Scottish Government. As such, the information requested is not held by the Scottish Government and would have to be obtained directly from individual local authorities or from COSLA.

Scottish Local Government Financial Statistics is an annual publication providing a comprehensive overview of financial activity of Scottish local authorities in 2019-20 based on authorities' audited accounts.

I refer the member to the answer to question S6W-02838 on 21 September 2021. All answers to written Parliamentary Questions are available on the Parliament's website, the search facility for which can be found at https://www.parliament.scot/chamber-and-committees/written-questions-and-answers .

Emerging data suggests that some individuals with suppressed immune systems may not mount a full immune response to COVID-19 vaccination.

The multi-centred OCTAVE study led by colleagues from Glasgow University published their preliminary findings with widespread media coverage. The study funded by the UK Research and Innovation (UKRI) Medical Research Council (MRC) was designed to evaluate the immune responses following COVID-19 vaccination in patients with immune-mediated inflammatory diseases including inflammatory arthritis and Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) (an auto-immune disease affecting small blood vessels) who have received Rituximab treatment, along with a host of other conditions with various degrees of immunosuppression.

Initial findings suggest that in total about 40% of those across the patient groups studied produced a low antibody response to two doses of COVID-19 vaccine, and the proportion varied depending on the nature of the immune impairment.

The OCTAVE group presented their findings to the Joint Committee on Vaccination and Immunisation (JCVI) and the Committee took into account these findings to make their recommendation on a third primary dose of COVID-19 vaccine for severely immunocompromised people.

A second study called OCTAVE DUO, led by the same researchers and also funded by UKRI, is examining whether a third dose will give a stronger immune response in people with impaired immune systems.

Information about these studies is available at: Vaccine responses in patients with impaired immune systems – UKRI

New study tests third jab for people with weakened immune systems – UKRI

The COVID pandemic has inevitably affected A&E attendance and the pressure is being felt across the UK. Our NHS staff have faced unprecedented pressures over recent weeks as they work tirelessly and consistently to respond to the pandemic whilst continuing to provide vital treatment and optimal patient care. We are in daily contact with every Board, including NHS Forth Valley, and are monitoring the situation closely.

The significant pressures currently presenting in Health Boards, including NHS Forth Valley, are primarily as a result of reduced capacity due to infection control, staffing pressures as a result of self-isolation and annual leave, and an increase in attendances to A&E by those who are much sicker and require higher levels of care.

In July, NHS Forth Valley received their share of the additional £12 million in funding for Boards to support non-COVID emergency care by increasing staffing resource, recruitment is underway.

We are in daily contact with NHS Forth Valley and continue to support improvement work with the Board and the Health & Social Care Partnerships to minimise delays for patients no matter where they are in the system.